Increased AUC w/ cyclosporin. May increase INR w/ vit K antagonist eg, warfarin. Increased C
max & AUC w/ gemfibrozil. Decreased plasma conc w/ antacid susp containing Al & Mg hydroxide. Decreased AUC
0-t & C
max w/ erythromycin. Increased AUC of ethinyl estradiol & norgestrel. Increased risk of myopathy w/ gemfibrozil, other fibrates & lipid-lowering doses (>1 g daily) of niacin.